“If you want something you’ve never had, you’ve got to do something you’ve never done before.”

“I hope that we shall crush in its birth the aristocracy of our monied corporations which dare already to challenge our government to a trial of strength, and bid defiance to the laws of our country.”

“I wish that all nations may recover and retain their independence; that those which are overgrown may not advance beyond safe measures of power, that a salutary balance may be ever maintained among nations, and that our peace, commerce, and friendship, may be sought and cultivated by all. It is our business to manufacture for ourselves whatever we can, to keep our markets open for what we can spare or want; and the less we have to do with the amities or enmities of Europe, the better. Not in our day, but at no distant one, we may shake a rod over the heads of all, which may make the stoutest of them tremble. But I hope our wisdom will grow with our power, and teach us, that the less we use our power, the greater it will be.”

“Neither Pagan nor Mahamedan nor Jew ought to be excluded from the civil rights of the Commonwealth because of his religion. -quoting John Locke's argument.”

“Altho' I rarely waste time in reading on theological subjects, as mangled by our Pseudo-Christians, yet I can readily suppose Basanistos may be amusing. Ridicule is the only weapon which can be used against unintelligible propositions. Ideas must be distinct before reason can act upon them; and no man ever had a distinct idea of the trinity. It is mere Abracadabra of the mountebanks calling themselves the priests of Jesus. If it could be understood it would not answer their purpose. Their security is in their faculty of shedding darkness, like the scuttlefish, thro' the element in which they move, and making it impenetrable to the eye of a pursuing enemy, and there they will skulk.

“Bigotry is the disease of ignorance, of morbid minds; enthusiasm of the free and buoyant. Education and free discussion are the antidotes of both. We are destined to be a barrier against the returns of ignorance and barbarism. Old Europe will have to lean on our shoulders, and to hobble along by our side, under the monkish trammels of priests and kings, as she can. What a Colossus shall we be when the Southern continent comes up to our mark! What a stand will it secure as a ralliance for the reason & freedom of the globe! I like the dreams of the future better than the history of the past. So good night. I will dream on, always fancying that Mrs Adams and yourself are by my side marking the progress and the obliquities of ages and countries.”

“We seem not to perceive that, by the law of nature, one generation is to another as one independent nation is to another.”

“The probable accumulation of the surpluses of revenue beyond what can be applied to the payment of the public debt... merits the consideration of Congress. Shall it lie unproductive in the public vaults?...Or shall it rather be appropriated to the improvements of roads, canals, rivers, education, and other great foundations of prosperity and union”

“The doctor of the future will give no medicine, but will interest his (sic)patient in the care of the human frame, in diet and in the cause and prevention of disease”

“The whole art of government consists in the art of being honest. Only aim to do your duty, and mankind will give you credit where you fail.”

“The most fortunate of us, in our journey through life, frequently meet with calamities and misfortunes which may greatly afflict us; and, to fortify our minds against the attacks of these calamities and misfortunes should be one of the principal studies and endeavors of our lives. The only method of doing this is to assume a perfect resignation to the Divine will, to consider that whatever does happen, must happen; and that, by our uneasiness, we cannot prevent the blow before it does fall, but we may add to its force after it has fallen. These considerations, and others such as these, may enable us in some measure to surmount the difficulties thrown in our way; to bear up with a tolerable degree of patience under the burden of life; and to proceed with a pious and unshaken resignation, till we arrive at our journey's end.”

“Do not be too severe upon the errors of the people, but reclaim them by enlightening them.”

“I hold it that a little rebellion now and then is a good thing, and as necessary in the political world as storms in the physical.” 

“I sincerely believe the banking institutions having the issuing power of money, are more dangerous to liberty than standing armies.”

“Some men look at constitutions with sanctimonious reverence, and deem them like the ark of the covenant, too sacred to be touched. They ascribe to the men of the preceding age a wisdom more than human, and suppose what they did to be beyond amendment. I knew that age well; I belonged to it, and labored with it. It deserved well of its country. It was very like the present, but without the experience of the present; and forty years of experience in government is worth a century of book-reading; and this they would say themselves, were they to rise from the dead. I am certainly not an advocate for frequent and untried changes in laws and constitutions. I think moderate imperfections had better be borne with; because, when once known, we accommodate ourselves to them, and find practical means of correcting their ill effects. But I know also, that laws and institutions must go hand in hand with the progress of the human mind. As that becomes more developed, more enlightened, as new discoveries are made, new truths disclosed, and manners and opinions change with the change of circumstances, institutions must advance also, and keep pace with the times. We might as well require a man to wear still the coat which fitted him when a boy, as civilized society to remain ever under the regimen of their barbarous ancestors.”